It happened at 2:50 a.m. on West 21st Street at Sixth Avenue.
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Plainclothes officers who were wearing NYPD windbreakers were working inside Club Doux when a bouncer told them a robbery was taking place in front of the club.
When the officers went outside and tried to intervene, police said the suspects fired at them.
The officers returned fire. No one was struck.
Two suspects fled in a silver Audi Sedan last seen heading westbound on West 21st Street, towards Seventh Avenue.
The suspects were generally described as wearing black hoodies.
Police found shell casings outside the nightclub.
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It happened at the same location where a man was shot and a police cruiser struck by gunfire last week, on July 18.
In the hours after shots were fired, police scoured nearby buildings and rooftops.
They took one person into custody in a nearby building during the search, found to be clinging to a fire escape.
He is being questioned at the 13th Precinct, and detectives are looking into any possible connection in the shots fired.
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No charges have been filed.
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