The crash happened just after 3 p.m. near 38 Calvert Dr. in Monsey.
Officials say 2-year-old girl was struck by a Honda Odyssey and had life-threatening injuries.
She was taken to Nyack Hospital where she later died from her injuries.
Police said the driver of the vehicle, a 21-year-old resident of Monsey, was not injured, remained on the scene and is cooperating with the investigation.
Police said there are no criminal charges at this time.
The crash remains under investigation by the Ramapo Police Crash Investigation Unit.
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