Around 2:30 a.m., police responded to Henderson Avenue in the West Brighton section, where they found a man shot in the right torso.
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Shamel Matthews, 21, of Staten Island, was taken to Richmond University Medical Center, where he was pronounced dead.
Authorities say Matthews was in a dispute with three unknown men was he was shot. They fled the scene.
Police have arrested Shaun Plair, 25, of Staten Island, and charged him with murder, criminal use of a firearm and criminal possession of a firearm.
The investigation is ongoing.