The four-alarm fire broke out shortly after 12:30 p.m. at a very large warehouse on Columbia Street on the Red Hook piers.
First responders arrived within minutes, and were met with fire blowing out the roofs of multiple areas.
FDNY officials say the blaze was originally in three bays, but it spread quickly due to the wind, and ultimately burned through eight to 10 bays.
"The weather was definitely a factor, with the wind carrying the embers throughout this building and catching fire to multiple other bays," said FDNY Chief of Operations Kevin Woods.
Officials say the bays contained a variety of products, including different types of refrigeration material, food, household items, and manufacturing products.
Firefighters were able to put the fire out, and no injuries were reported.
Officials say upwards of 25 businesses were operating in the warehouse.
The New York City Department of Buildings is on site assessing the structural integrity of the warehouse.
The cause of the fire is under investigation.
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