According to a spokesperson for Barclays, a group of fans without tickets tried to force their way into the Power 105.1's Powerhouse show featuring musicians including The Weeknd, Migos, French Montana and Cardi B.
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After the incident, the venue shut the doors and would not allow anyone else inside, even ticketed customers.
EMS treated two people on-scene after they suffered burns in their eye.
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According to witnesses, pepper spray was used on the crowd, buts it's unclear where it came from.
This video posted on social media showed the crowd rushing inside:
The Barclays Center says that "For ticket holders whose tickets were not scanned, refunds will be available at the point of purchase."