A captain and officer conducting a tour around 12:30 a.m. discovered the man unresponsive in his cell at the George R. Vierno Center, according to the New York City Department of Corrections.
First responders attempted to resuscitate the man on scene, but he was pronounced dead just before 1 a.m.
"On behalf of the NYC Department of Correction, I extend my heartfelt condolences to the individual's family, friends, and loved ones during this incredibly difficult time. Any loss of life in our custody is a tragedy, and we are committed to a full review of the circumstances surrounding this incident," said NYC Correction Commissioner Lynelle Maginley-Liddie in a statement.
The medical examiner's office will determine the cause of the death.
----------
* Get Eyewitness News Delivered
* More Manhattan news
* Send us a news tip
* Download the abc7NY app for breaking news alerts
* Follow us on YouTube