A blue Audi, driven by a 65-year-old man, was travelling southbound on Bell Boulevard just before 9:30 p.m. Friday.
Investigators say the Audi collided with a Toyota driven by the 28-year-old man, with the woman and child riding inside.
The 28-year-old man was pronounced dead at a local hospital.
The woman and 5-year-old boy were hurt but are in stable condition.
The Audi driver was uninjured and remained on scene.
No arrests have been made, and the NYPD Highway Collision Investigation Squad is investigating.
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