New York State Police responded to the collision just north of Bay Parkway around 11:30 p.m. on Wednesday.
According to state authorities, Timonthy Peter Reid, of Huntington, was driving a 2020 Nissan Rogue southbound in the northbound lanes of the Meadowbrook State Parkway when he struck 28-year-old Byron DeJesus Alvizures Cifuentes who was traveling in the correct direction.
Police say both Reid and Alvizures Cifuentes were the only people in their vehicles.
Both Reid and Alvizures Cifuentes were pronounced dead at the scene.
Police say the scene of the crash was cleared ahead of Thursday morning's commute.
The NY State Police is asking anyone who saw or has information about the accident to call (631) 756-3300.
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