Police say two teenagers were walking eastbound across Station Road at the intersection of Patchogue Avenue when a white, midsize Jeep SUV hit them at 9:38 p.m.
The vehicle then fled south toward Montauk Highway, police said.
D'Ajiah Mitchell, 15, was transported to Stony Brook University Hospital with serious injuries.
Kevin Reese, 14, was transported to NYU Langone Hospital - Suffolk County with minor injuries.
Police believe the car sustained damage to the front left corner, including the headlight.
----------
* Get Eyewitness News Delivered
* More Manhattan news
* Send us a news tip
* Download the abc7NY app for breaking news alerts
* Follow us on YouTube