The highlight of the holiday will be the annual Macy's 4th of July fireworks spectacular along the East River.
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The show, scheduled to start at 9:25 p.m., will feature more than 56,000 pyrotechnic shells, 22 different hues and the New York debut of "pyro-writing" in the sky, all synchronized to patriotic tunes performed by the United States Air Force Band.
More than a million people are expected to watch the display.
The NYPD will be deploying its enhanced counterterrorism unit, including monitoring more than 9,000 video feeds from cameras across the city.
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This is also the first year the NYPD will be utilizing its Critical Response Command, heavily armed and well-equipped officers who can respond to a major incident at a moment's notice.
There will be NYPD and Coast Guard boats in the water, helicopters in the air and thousands of NYPD officers on the streets.
Police will also be using bomb-sniffing dogs who can detect radiation or chemicals.
There is no known specific or credible threat against the city for the 4th of July.
Click here for a list of fireworks displays throughout the Tri-State area.