The incident was reported on 37th Avenue and 82nd Street in Jackson Heights just after 5 p.m.
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Police say a 48-year-old man driving a minivan southbound on 82nd Street jumped the curb and slammed into a building.
A 34-year-old man walking on the sidewalk was struck. He was taken to Elmhurst Hospital in critical but stable condition.
Witnesses also said a child was taken away on a stretcher in an ambulance. It is believed she was a passenger in the minivan, but the extent of her injuries was not yet known.
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The driver of the minivan was said to be OK after the incident and stayed on the scene.
Police are investigating the cause of the accident.
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