The fatal fire happened in the South Ozone Park section around 12:30 a.m. Saturday.
Citizen app video shows heavy flames and smoke shooting from the structure on 133rd Street.
An Uber driver says he was driving by and saw the flames and jumped out of his car to help a dog that was inside.
"It looks like the dog had difficulty breathing and an injury on the back," the driver told Eyewitness News. "I have dogs myself. I have five dogs. I would want somebody to do this for my dog if I'm not around."
While the dog was rescued from the fire, it was not able to overcome its injuries and died a short time later.
After the initial fire investigation, officials believe the flames started in the victim's kitchen.
The FDNY does not consider the fire to be suspicious.
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