Audience members waited outside with tickets in hand, receiving instructions from security as they made their way into the theatre, some waiting a long time to see a masterpiece of a performance.
Inside, laughter broke out as one of the show's creators joked, "In New York City there's no such thing as a little fire ... it just doesn't happen."
For some theatergoers, the reopening marked the end of an unexpectedly long wait.
"We booked our tickets six months ago," said audience member Geri Baca. "Did not know about the fire and then a co-worker of mine said, 'oh, what day are you going?' And I said the 27th. And he's like, 'oh they're opening on the 27th.' And I'm like hallelujah!"
Since its 2011 debut, "The Book of Mormon" has become one of Broadway's most successful productions, earning nine Tony Awards and drawing repeat visitors.
"The music is great. The acting was great. They insult everybody. We loved it," said Artie, who attended with Rona for their second viewing.
The night carried a more serious tone as well. Show creator Matt Stone paused the festivities to acknowledge the first responders who helped save the century-old theater.
"I really wanted tonight in front of everyone to thank the FDNY," he said to applause.
Manhattan Borough President Brad Hoylman-Sigal joined Stone onstage to present a proclamation honoring the FDNY's "heroic efforts to save this 100-year-old theatre just three weeks ago."
The fire caused significant damage to the theater's spotlight booth, but firefighters and repair crews worked quickly enough to keep the production's 15th anniversary on track.
On reopening night, they were celebrated as the true stars of the show.