The attack happened in the stairwell at Martin Van Buren High School on Hillside Avenue.
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One student was stabbed in the stomach and shoulder and the other only in the shoulder.
Neither suffered life-threatening injuries but both were taken to Long Island Jewish Medical Center where they were said to be stable with superficial injuries.
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A 17-year-old boy was charged with criminal possession of a weapon, according to police.
Two other persons of interest are in custody.
Martin Van Buren High School was locked down after the incident and the Department of Education released the following statement:
"The safety and wellbeing of our students is our absolute top priority. NYPD immediately responded to an incident at the school. Students were placed on a brief soft lockdown and have now been dismissed. We will be providing additional emotional supports to any student who needs it."
A knife was also recovered at the scene.
Few other details were released.
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