The motorcycle crashed into a 4 door sedan traveling on Cross Bay Boulevard as it made a left turn at 162nd Street, police said.
Both people were thrown from the motorcycle.
The passenger on the motorcycle, identified as 33-year-old Elvin Veras-Polanco, was killed, police said.
The 28-year-old man driving the motorcycle was listed in critical condition.
The driver of the sedan, a 19-year-old woman, and her two passengers suffered minor injuries.
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