Police say the victim was in the crosswalk at West 60th Street and Broadway when she was hit around 7:30 a.m.
She sustained serious head trauma and is in critical condition at Mount Sinai Morningside Hospital.
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The 23-year-old driver remained at the scene and is being questioned, and charges are expected.
The crash also created traffic backups in the area.
Related: Revel shuts down service in New York City after 2nd scooter death in a week
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