It began at about 11:10 p.m. on East 173rd Street in the Soundview section.
Two women were shot, one in the leg and the other in the back and arm. The injuries are not considered life-threatening.
The women ran into a deli seeking help.
Moments later about a half block away, a 31-year-old women fleeing the gunshots ran into the street holding her 3-year-old son and both were hit by a car.
The driver remained on the scene.
The mother and child sustained non-life threatening injuries and were taken to Jacobi Hospital.
The two men who opened fire remain at large.