The race traces the heroic steps he took when he abandoned his truck in Brooklyn and ran to the towers of the World Trade Center.
Thousands of people ran from Brooklyn to Lower Manhattan to honor the lives lost on 9/11.
The race kicked off at the entrance to the Brooklyn-Battery Tunnel.
All the money raised in Sunday's event will be for the Stephen Siller Tunnel to Towers Foundation, supporting first responders and wounded veterans of the Iraq and Afghanistan wars.