Police say the truck carrying gasoline crashed at about 6 a.m. between Exits 23 and 24 northbound on Interstate 91 in Rocky Hill.
The entire truck quickly went up in flames.
No one was injured but some residents in the area were evacuated due to heavy fire and smoke.
Both sides of the highway were closed for several hours.
Later in the morning, a tractor-trailer veered off I-91 in Wallingford, taking down power lines.
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