The incident was reported at 105th Street and 3rd Avenue after 8 a.m.
Officials say the victim got into a dispute with two other teenagers that she knows.
During the fight, one of the girls pulled out a knife and stabbed the victim in the hip.
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She was taken to Harlem Hospital and was said to be serious but stable.
Police said they are still searching for the two other girls.
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Few other details were released. The investigation is ongoing.
Eyewitness News is tracking crime and safety across New York City and in your neighborhood
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