It happened before 5:15 a.m. in the Bedford Park section of the Bronx at 226 E. 203rd St.
The 40-year-old woman was shot multiple times in the torso and was pronounced dead at a local hospital, police say.
Mejia Castillo, 37, was charged with murder, assault, and criminal possession of a weapon. Police say he is the boyfriend of the victim.
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The victim's nephews, ages 8 and 16, were shot once in the arm and buttocks respectively, police say. They were taken to a local hospital and are in stable condition.
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