The fire broke out juat after 1 a.m. in the Crestwood Apartments in Wallkill. Strong winds fanned the flames and caused the fire to spread quickly.
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By the time firefighters arrived at the scene, the entire building was engulfed.
This is cellphone video showing the fire:
It took firefighters several hours to bring the fire under control.
Tuesday afternoon, town officials inspected what was left of the building -- the center unit in the complex.
More than a dozen families have been displaced, and two residents were taken away on stretchers. Those are the two in critical condition. Three others were treated for injuries in the fire.
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The building has since been condemned, and the Red Cross is helping displaced residents.
Stay with abc7NY for the latest on this developing story.