Pat Sajak and Vanna White with series executive producer Harry Friedman as they take a spin through Wheel history, reliving memorable moments.
They will also discuss how the game show is produced on a daily basis, as well as how the program has evolved through the decades.
The evening will feature classic clips, and they will take questions from the audience.
Eyewitness News entertainment reporter Sandy Kenyon is serving as moderator.
The discussion will begin at 6:30 p.m. on Wednesday.
The event kicks off the Wheel of Fortune: 35 Years as America's Game exhibit at the Paley Center for Media, located on West 52nd Street between Fifth an Sixth avenues in Manhattan. It features interactive games, photos, memorabilia, and videos - all on display until December 3.
If you'd like to get tickets to the event and the exhibit, go to paley.me/wheel.