The fire was reported at 142 Bleecker Street just before 6 p.m.
GMT Tavern, located on the corner of Bleecker and LaGuardia Place, was ruined in the blaze. Neighbors say the popular watering hole shut down during the pandemic and only reopened one month ago.
4 firefighters injured in Greenwich Village apartment fire
"It's heartbreaking, to see all your work, everything you worked for this year, you re-open and it's down to ashes," customer Diana Defosse said.
FDNY officials said the fire may have started in the restaurant, but the cause is under investigation.
Firefighters arrived within three minutes but the smoke was already intense and the flames were inside the ducts.
Fortunately, residents on the upper floors were able to evacuate the building without injuries.
Officials said four firefighters were injured, and three of those injuries were considered minor.
One firefighter's injuries were said to be more serious, but not life-threatening.
Smoke could be seen pouring out of the building from miles away.
ALSO READ | Canada goose protecting its brood causing problems at New Jersey diner
Goose protecting its brood causing problems at NJ diner
----------
* Get Eyewitness News Delivered
* More Manhattan news
* Send us a news tip
* Download the abc7NY app for breaking news alerts
* Follow us on YouTube
Submit a News Tip