Police say the two gunmen started firing on Burke Avenue in the Bronx just after sunset from the back seat of an SUV toward a veterans health facility on the corner.
Four people were shot, including a 59-year-old woman and a 15-year-old boy. Police do not believe they or another 26-year-old man were the intended targets.
Authorities say an 18-year-old man carrying a fake handgun was shot in the head.
It's not yet clear who or what the gunmen were aiming at, but officials say the 18-year-old has no criminal history.
The incident was the third shooting this week with multiple victims.
In Harlem on Monday night, four people were shot while standing outside a bodega.
On Tuesday, three people were shot on West 38th Street in what police called a gang involved shooting.
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