The fire started just before midnight Saturday in the back of a restaurant at 6 Chatham Square before spreading to other parts of the building, FDNY officials said.
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The four-story building also contained several apartments above the restaurant.
The fire escalated to a fifth alarm as roughly 39 unites and 170 firefighters responded to the scene.
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Five firefighters suffered minor injuries and were taken to nearby hospitals for evaluation.
Fortunately, there were no injuries to residents in the building.
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The fire was placed under control just after 6 a.m.
The cause of the fire is under investigation.
This is breaking news. This story will be updated as more information becomes available.
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