The 22-year-old driver apparently failed to stop at 111th Avenue and 117th Street at around 4:30 a.m. on Monday.
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He crashed into a vehicle occupied by two men.
A 64-year-old man was killed, and a 71-year-old is in serious condition at Jamaica Hospital.
The driver was not seriously injured and was taken into custody on suspicion of driving while impaired.
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