Woodbridge Township residents said they heard a loud bang and saw flames shooting out of the home on Vernon Way around 9:50 a.m.
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When firefighters arrived on scene, the home was engulfed in flames. One neighbor said the entire bottom floor of the house was engulfed in a matter of seconds.
About seven fire departments responded and the blaze was contained in less than an hour, police said.
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Six adults were hospitalized with serious burns. Seven juveniles were also hurt, most of them suffering from smoke inhalation.
Investigators said the fire began in the basement.
The cause of the blaze is unknown, and an investigation is ongoing.
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