Officials say it happened on Park Avenue just before 6 p.m.
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The victim was pronounced dead at the scene.
Authorities have not released the man's identity.
No arrests have been made.
Earlier this month, 16-year-old Letrell Duncan was fatally shot in East Orange as school was letting out for the day.
The gunfire erupted in a residential neighborhood near several schools, including the Edward T. Bowser School of Excellence on Lincoln Street.
It happened just after 3 p.m. Monday, Oct. 3, as many of those schools were letting out for the day.
Investigators say the 16-year-old was shot multiple times at the corner of Lincoln Street and Park Avenue.
He was taken to University Hospital in Newark, where he was pronounced dead.
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