Police responded to 1521 Dean St. in the East Flatbush section around 6:25 p.m.
Officers found a 32-year-old woman lying in the roadway with head trauma.
They also found a 6-year-old boy who suffered cuts to his face.
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The woman was taken to Interfaith Medical Center, where she was pronounced dead.
The child was also taken to the hospital and is in stable condition.
A preliminary investigation revealed that the woman and child were riding on a motorized scooter when they were struck by a Ford Escape SUV as it was exiting a driveway.
The driver remained on scene and was not injured.
The investigation is ongoing.
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