Firefighters were called to the scene on Atlantic Avenue just after 7:30 a.m. Saturday.
Video from Citizen App showed heavy smoke and flames pouring out of the building in Cypress Hills Saturday morning.
Eyewitness News is told the fire started in a single-story auto repair shop.
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The roof partially collapsed after firefighters arrived and began working to control the blaze.
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Three firefighters were being treated for injuries described as minor sprains and strains.
The cause of the fire is under investigation.
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