The victim was walking southbound on Fifth Avenue when he was hit by a Toyota RAV4 shortly after 9:00 p.m.
The victim was rushed to nearby Harlem Hospital, where he was pronounced dead.
The incident marks the second fatal hit and run in Manhattan in two days.
A bicyclist was killed by a Toyota minivan that sped away from a police stop, striking the victim at W. 155th Street and St. Nicholas Avenue Saturday night.
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