One of the contestants will be singer, television star and social media sensation JoJo Siwa. And in a U.S. "Dancing with the Stars" first, she'll be dancing with a female professional dance partner.
Siwa, an 18-year-old who has said she identifies as gay and queer, said the same-sex pairing signals to viewers that it's OK to be your true self. She named Lindsay Arnold, Jenna Johnson and Britt Stewart as among the show's regular pros she'd like to be paired with.
"I think it breaks a wall that's never been broken down before," she told an online gathering of the Television Critics Association. "It's normal for a girl to dance with a guy, and I think that's really cool, but it's really special that now not only do I get to share with the world that you get to love who you love, but also you get to dance with who you want to dance with."
Siwa noted that among the things to be worked out with her partner are who leads, how do they dress and what shoes do they wear.
"It's going to give so much to people out there, people of the LGBTQ community, everyone, people who feel just a little different," she said. "I want to make it OK for the people who come after me."
Host Tyra Banks told Siwa she's proud of the teenager and the show for allowing the pairing to happen.
"I think it's going to save lives," Banks said. "I think it's going to change lives, and it's going to make a lot of noise, and the noise that needs to be made."
Siwa said when she was first approached, show executives asked if she wanted to be paired with a man or woman. She has already reassured her girlfriend, Kylie Prew, that despite any chemistry she has with her on-air partner, it's completely platonic.
"She was like, 'Love, you are going to be incredible,'" Siwa said. "She has been nonstop supportive."
Siwa first gained fame on a dance competition show produced by Abby Lee Miller of "Dance Moms."
"I just want to do really good," she said, adding that she's already been tanning daily.
"I'm traumatized as a child getting spray tans for dance competitions," Siwa said.
Joining Siwa in the ballroom: Three-time Olympic medalist Suni Lee. She recently won the gold medal as the all-around champion in women's gymnastics at the Tokyo Olympics.
The 18-year-old from Minnesota will juggle online classes from Auburn University while participating on the Los Angeles-based show.
"I can express myself, which I'm excited for, because in gymnastics you can't really do that, especially when you're training for so much and it's just a very intense kind of environment," Lee said. "I'm excited to kind of let loose and just have fun."
Len Goodman returns to the judging panel after taking last season off, joining Carrie Ann Inaba, Bruno Tonioli and Derek Hough.
Banks is back for her second season after replacing Tom Bergeron, whose legion of supporters were critical of the former model's performance.
"Be angry and watch," Banks said. "Change is hard, but change is necessary. Change must happen. We must continue to evolve."
The remaining cast members are set to be revealed Wednesday, Sept. 8. The season premiere airs live Monday, Sept. 20 on ABC.
The Associated Press contributed to this report.