The suspects were arrested as part of a joint NYPD/FBI operation at the East River Houses.
Suspects were brought out by New York City Police Department officers and federal agents just after 5 a.m.
The suspects are all accused of being involved in narcotics and firearms dealing.
They will be arraigned later Tuesday before a federal judge in Lower Manhattan.
Feds and NYPD arrest more than 30 alleged gang members in NYC; suspected in 12 murders and more than 24 shootings pic.twitter.com/uEugA7RkTN— Kristin Thorne (@KristinThorne) April 19, 2016
The arrests are the culmination of an investigation ongoing for several years, targeting the East River houses and other city run projects.
The neighborhood has seen a recent spike in gang activity and shootings, most recently the fatal shooting of 16-year-old Chico Tavarez outside the Jefferson Houses. Law enforcement is aware of an ongoing dispute between members of the Jefferson Houses and nearby Wagner Houses, both city-run housing complexes.