Crews responded to a fire inside a home at 69-37 Hillmeyer Avenue just before 6:30 a.m.
After they put out the fire, firefighters discovered the unconscious 9-year-old. Police said he had trauma to the body.
He was taken to the hospital where he was pronounced dead.
The FDNY said three other people suffered minor injuries.
The four apartments consisted of two family homes attached to each other. All four families lost their homes in the fire.
Neighbors shared video of the fire and flames and smoke could be seen coming from the second floor apartment on the right.
The owner of two of the apartments said he was very upset when he heard the child died.
"He's a very nice kid, all the time, you know, working, I'd see him if a tenant had a problem or anything like that, I came in, he was a really nice kid, I mean it's really sad," Yehezkel Fishbach said.
"It's a tragedy man, a little boy's not supposed to die like that," neighbor Dennis Martinez said. "Everybody get out of the house, and just left him in there, something is wrong with the picture to me."
Police are investigating the blaze and said it is considered suspicious, though it wasn't yet clear why.
It is not yet known if anyone else was home at the time of the fire.
The Fire Marshal will determine the cause of the fire.
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