Several drive-thru testing sites have been up and running for weeks around the Tri-State area, but there have been fewer walk-in sites.
Many New Yorkers don't own a car and it's been lower-income minority communities that have seen the most infections and death from COVID-19.
In addition to East New York, there's another one opening in Vanderbilt on Staten Island Friday and also in the Morrisania section of the Bronx.
Mayor Bill de Blasio says the locations chosen were strategic.
"This is about how we end this crisis. Not so much just, you go someplace and you get a test that tells you at one point in time how you're doing. I understand why people want that, but we've got to do something more strategic for everyone to get out of this crisis," the mayor said.
In the coming days, more testing sites will open in Jamaica and Harlem. The tests are done by appointment only.
MORE CORONAVIRUS COVID-19 COVERAGE
UPDATES
Grieving the lost: Tri-State residents who have died
New York state
New Jersey
Connecticut
Long Island
RESOURCES
Where are the testing centers
See how our communities are making a difference
Free educational resources for parents and children
How you can help victims of coronavirus
RELATED INFORMATION
Share your coronavirus story with Eyewitness News
Stimulus check scams and other coronavirus hoaxes
Coronavirus prevention: how clean are your hands?
Centers for Disease Control and Prevention on coronavirus
Total count of NYC COVID-19 cases based on patient address