The deputies found more than 164 people inside of a building on 243rd Street in Rosedale around 2:45 a.m.
Attendees apparently used a rear alleyway to enter the illegal club.
Officials say besides violating restrictions in place because of the coronavirus pandemic and having no liquor license, the illegal club also violated fire codes.
Deputies arrested five people and charged them with multiple offenses.
The Sheriff's Office has shut down a number of illegal clubs and parties recently.
Last week, a woman was seriously injured in a shooting outside an illegal club in the Bronx after she spurned the gunman's advances.
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