At least 10 people were injured the pileup, which occurred amid heavy fog and low visibility about 40 miles north of Bakersfield.
The suspects in the killing of Aiden Leos, the 6-year-old who was shot on a Southern California freeway last month, have been charged.
It's unclear how long it will take to repair the roadway. In the meantime, the highway is closed.
Officials are investigating after a PG&E pickup truck was apparently shot at while driving on I-5 south of Colusa County.
A California Highway Patrol officer and a suspect were killed and two officers were seriously injured in a gun battle in Riverside, officials say.
A semi-truck hauling a payload of beer veered over the side of a freeway on-ramp and crashed in California, spilling hundreds of cans on a hillside and the street below.