The major takedown involved five different criminal operations in the South Bronx.
President Donald Trump's acting attorney general on Thursday signed an order reclassifying state-licensed medical marijuana as a less-dangerous drug.
The DEA says it seized loads of narcotics, weapons, and enough fentanyl to kill millions.
A judge is expected to sentence OxyContin maker Purdue Pharma to forfeit $225 million to the Justice Department on Tuesday, clearing the way for the company to finalize a settlement of thousands of lawsuits it faces over its role in the opioid crisis.
President Donald Trump on Saturday directed his administration to speed up reviews of certain psychedelic drugs, including ibogaine.
The massive takedown in the Bronx involved dismantling, what officials called, three fentanyl packaging mills.