The Office of Emergency Management in Ramsey posted on social media in part to 'stay indoors and close all windows and garage doors.'
Officials say a beehive was accidentally disturbed in the area of Martis Avenue and Elizabeth Avenue, then dispersed throughout the area.
The bees are believed to be aggressive.
Officials say a beekeeper and his wife were hospitalized after the man's colony became aggressive and swarmed part of the town.
Ramsey Police Chief Bryan Gurney told The Record it's unclear what angered the colony, but he was concerned and planning to subdue or destroy the bees.
The beekeeper and his wife were taken to an area hospital but were not identified.
Srini Abbaraju, a New Jersey-based bee remover, told The Record it's rare for managed colonies to attack and that they usually sting if disturbed.
(The Associated Press contributed to this report.)