Scott Clemmensen stopped 35 shots, and Brian Gionta and Travis Zajac also scored for New Jersey, 6-5 since goalie Martin Brodeur was sidelined by a torn biceps.
Jay Bouwmeester added a goal for Florida.
Florida goalie Tomas Vokoun was pulled in favor of Craig Anderson following the first period after allowing two goals on 12 shots. Anderson stopped 22 of 25 shots.
It was New Jersey's second victory over Florida in less than a week. The Devils beat the Panthers 3-1 victory at home on Nov. 20.
Oduya scored on a wrist shot that went between Anderson's pads and his glove.
New Jersey led 2-0 before Bouwmeester got Florida on the board with 2:19 left in regulation on his first goal of the season.
Gionta opened the scoring 5:33 in with a power-play goal. He tipped Oduya's centering pass through Vokoun's legs.
Zajac made it 2-0 at 18:25 when he took a drop pass from Jamie Langenbrunner and fired a wrist shot that went through Vokoun's legs and bounced in off the right post.
New Jersey completely dominated the first half of the game and had a 25-7 shot advantage at one point in the second period. The shots ended up at 37-37.
Notes: Florida's first shot on goal in the second period came with 12:02 remaining. ... New Jersey C John Madden missed his third consecutive game because of a foot injury. ... New Jersey D Mike Mottau missed the game while serving the second of a two-game suspension for an elbowing incident against the Islanders.
