The driver's death has been ruled a homicide.
Police say he was stabbed in the chest shortly before he got behind the wheel and lost control of his SUV in Brownsville.
The suspect has been identified as 51-year-old Kenneth Risher of Brooklyn, who remains on the run.
Police believe the driver, 44-year-old Sean Lewis, was a loan shark trying to collect money from Risher.
13-year-old Kira Goddard had been hanging out with her friends when the tragic crash claimed her life.