Troopers say 27-year-old Tiffany Lesane was driving a dark blue Ford Focus on Interstate 84 in Wallkill around 3:15 p.m. Friday when she traveled into an embankment in the center median and overturned.
Lesane was not wearing a seat belt and was ejected from the vehicle.
She was pronounced dead at the scene.
Her son was treated at Westchester Medical Center for a head injury.
Troopers say witnesses reported that it appeared Lesane was involved in a road rage encounter with an unidentified light blue vehicle traveling in the same direction.
Anyone with information is asked to contact state police in Middletown at 845-344-5300.
(The Associated Press contributed to this report)