Billy Wagner closed out the Mets' fourth win in the six-game rivalry. It was just the second time since interleague play started in 1997 that they've taken the season series.
Perez (6-5) limited the Yankees to one run and three hits in seven sharp innings. He retired the first 10 batters and wound up striking out eight without a walk.
Perez improved to 5-1 with a 2.61 ERA in six career starts against the Yankees, including a win last month at Yankee Stadium. How he pitches so well surely baffles the Mets and most everyone else - he had won only one of his previous seven starts since that victory in the Bronx.
In command the whole way, his lone blemish came when Wilson Betemit homered over the left-field bleachers with two outs in the seventh.
After Pedro Feliciano pitched a hitless eighth, Wagner took over in the ninth. For the first time on a humid, rainy afternoon, the crowd of 56,277 really got into the game, even more so after Derek Jeter led off with a single.
Wagner retired Alex Rodriguez on a long fly, got Jorge Posada on a grounder and struck out Betemit for his 18th save in 23 chances.
Darrell Rasner (4-6) managed to escape several early jams with a minimum of damage. Even so, he lost for the sixth time in seven starts.
Stuck in a season-long slump, Delgado struck again, two days after hitting two home runs and setting a Mets record with nine RBIs in a rout at Yankee Stadium.
Delgado drew a smattering of boos after he stranded two runners in his first at-bat, then turned around these jeers with a solo homer in the third estimated at 445 feet. His 14th home run banged off the scoreboard in right-center field and temporarily knocked out a panel of lights.
The Mets took a 3-0 lead in the sixth. Reliever Dave Robertson, averaging well more than a strikeout per inning in his two-year minor league career, made his debut in the majors and gave up a run on singles by Jose Reyes and Luis Castillo, a wild pitch and a sacrifice fly by David Wright.
Castillo barely beat out an infield hit with the bases loaded and two outs in the second for the game's first run. Rasner clenched his fist to signal out, but Castillo reached the bag just ahead of Jeter's snap throw from shortstop.
