Video posted to social media shows officers trying to forcibly remove demonstrators from the middle of Seventh Avenue.
Police say numerous arrests were made after some protesters blocked traffic.
The arrests made near 1 Polize Plaza were protesters who had gathered to wait for protesters that had been arrested in Times Square, and were being processed there.
A majority of the arrests were for disorderly conduct.
The protesters called for the abolishment of ICE.
Earlier in the week, protesters rallied outside 26 Federal Plaza in Lower Manhattan, where property in and around the building was vandalized.
RELATED | Federal building vandalized during 'Abolish ICE' rally in Manhattan
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