The winning ticket was sold at West Harlem Deli at 2040 5th Avenue and East 126th Street. The winner's identity is not yet known.
The other ticket was sold at Casey's convenience store in Redfield, Iowa, a rural community of about 800 people.
Each ticket is worth an annuitized $343.9 million, or $198.1 million cash.
The winning numbers were 8, 12, 13, 19 and 27, and Powerball 4.
Additionally, there were two New Jersey Lottery tickets sold that matched five of the five white balls drawn to win $1 million second prize. They were sold at the Marlton Shop Rite on West Route 70 in Marlton and Welsh Farm Deli & Convenience on Towne Center Drive in North Brunswick.
No one had hit the jackpot since August 11 when the $245.6 million prize went to a man from Staten Island, New York.
RELATED: Things you need to consider if you win a mega jackpot
The biggest all-time lottery jackpot was a $1.5863 billion Powerball prize in 2016, with the recent Mega Millions coming up just short at $1.5 billion. That jackpot was claimed by a single ticket sold in South Carolina.
RELATED: The 10 largest lottery jackpots of all time and their winners
Powerball is played in 44 states.
Odds of winning the Powerball jackpot is 1 in 292 million.
You can watch the next Powerball drawing here on abc7NY.com and our WABC Eyewitness News app on Saturday night.
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