Authorities responded to the victim's home at 218-44 Hillside Avenue just before 8 p.m. after family members were unable to reach her.
They found Maria Diaz lying unconscious and unresponsive in the bedroom with a laceration to her head.
She was pronounced dead at the scene.
It is unclear if there were any signs of forced entry or if anything was stolen.
Police say what appeared to be a machete was found at the scene.
No arrests have been made and the investigation is ongoing.
MORE NEWS: NY father-to-be killed, brother injured when gender reveal device explodes
* More Queens news
* Send us a news tip
* Download the abc7NY app for breaking news alerts
* Follow us on YouTube
Submit a News Tip