Juliet Germanotta, 39, is accused of pouring paint on the mural for the third time.
In July, there was a string of similar acts of people or groups targeting Black Lives Matter murals throughout New York City.
Video obtained by Eyewitness News shows the first vandal at Trump Tower in action:
At the time, Brooklyn Borough President Eric Adams said he wasn't surprised and thought the vandalism would have happened sooner.
"As I move throughout the communities, I hear the confrontations, the debates and now they are using the murals as a symbol of their frustrations," Adams said in July. "Pain is pain and people are just trying to find ways to express the pain they are feeling."
Charges against Germanotta in the most recent incident are pending.
RELATED | Black Lives Matter mural serves as powerful backdrop for NYC wedding
* Get Eyewitness News Delivered
* More New York City news
* Send us a news tip
* Download the abc7NY app for breaking news alerts
* Follow us on YouTube