5, including 2 doctors, charged in Matthew Perry's death investigation; 2 plead not guilty

LOS ANGELES -- Five people have been charged in connection with the ketamine death of "Friends" star Matthew Perry, federal officials in Los Angeles announced Thursday.

Three of the defendants, including a doctor and the actor's assistant, are in plea agreements for federal drug charges in connection with this death, while two others -- including a second doctor and a woman reportedly known as "The Ketamine Queen" who is accused of selling Perry the batch of ketamine that killed him, were arrested on Thursday, according to the Department of Justice.

U.S. Attorney Martin Estrada said investigators conducted a wide-ranging investigation following Perry's death in October 2023 that "revealed a broad, underground criminal network responsible for distributing large quantities of ketamine to Mr. Perry and others."

Defendants accused of taking advantage of Perry's addiction

The lead defendants in the case are Jasveen Sangha, 41, allegedly known as "The Ketamine Queen," and Dr. Salvador Plasencia, 42, a licensed medical doctor known as "Dr. P," the DOJ said.

The three others separately charged in the case include Dr. Mark Chavez, 54, a licensed medical doctor who admitted in court documents to selling ketamine to Plasencia; Eric Fleming, 54, who admitted in court documents that he distributed the ketamine that killed Perry; and Perry's live-in assistant, Kenneth Iwamasa, 59, who admitted in court documents to administering the ketamine on the day that Perry died, the DOJ said.

SEE ALSO: US attorney may consider charges against multiple people in Matthew Perry drug investigation

"These defendants took advantage of Mr. Perry's addiction issues to enrich themselves," Estrada said during a press briefing on Thursday. "They knew what they were doing was risking great danger to Mr. Perry, but they did it anyway."

Estrada said that in the fall of 2023, Perry, who has struggled with addiction in the past, "fell back into addiction, and these defendants took advantage to profit for themselves."

Plasencia allegedly worked with Chavez to obtain ketamine and with Iwamasa to distribute that ketamine to Perry. Over two months, they distributed approximately 20 viles of ketamine to Perry in exchange for $55,000 in cash, Estrada said.

"Plasencia saw this as an opportunity to profit off of Mr. Perry," Estrada said, noting that the doctor allegedly wrote in text messages, "I wonder how much this moron will pay," and that he wanted to be the actor's "go-to for drugs."

The vials cost the doctors $12 but they were selling them for $2,000 a vial to Perry, authorities said.

As a doctor, Plasencia "knew the danger of what he was doing" and allegedly told another patient that Perry was "spiraling out of control with his addiction," Estrada said.

"Nevertheless, he continued to offer ketamine to Mr. Perry," Estrada said.

Plasencia pleaded not guilty during his arraignment Thursday afternoon, appearing with shackled feet in a button-down shirt and slacks.

The government argued he shouldn't be able to run a clinic or treat any patients as a condition of his employment, claiming he acted as a "street-corner drug dealer after money and profit."

His attorney, Stefan Sacks, said that the doctor had already given up his Drug Enforcement Administration license and is unable to prescribe controlled substances. Sacks said the defendant has other patients in the community who rely on him and asked that the medical board weigh in before he is ordered to stop seeing patients entirely.

Judge Alka Sagar agreed to Plasencia's release on $100,000 bond and ordered him to relinquish his passport. The judge also mandated that a sign be posted in the clinic alerting all patients of the ongoing federal case, and that patients must sign a form each time consenting that they are aware. The next hearing has been scheduled for Oct. 8.

The other lead defendant, Sangha, is accused of selling 50 vials of ketamine for approximately $11,000 in cash over two weeks to Perry, working with Fleming and Iwamasa to distribute the drugs to Perry, according to Estrada. She is accused of selling Perry the batch of ketamine that killed him.

The indictment alleges that Sangha was additionally aware of the danger of ketamine after, years earlier, selling the drug to someone who hours later died from an overdose in August 2019. A family member of the victim sent a message to Sangha, telling her the cause of death was ketamine, according to the indictment.

Sangha also pleaded not guilty during her arraignment on Thursday, appearing in a green Nirvana sweatshirt with purple hair and shackles on her feet.

Sangha had initially appeared in court in March and was released on bond, though Judge Sagar revoked her bond on Thursday and remanded her to the custody of the U.S. Marshal.

The government noted during the arraignment hearing that Sangha, a citizen of both the U.S. and Great Britain, traveled lavishly following Perry's death, including leading up to her arraignment.

The judge said the evidence shows that Sangha has a "commitment to drug dealing" and "funds her lifestyle from drug sales," citing the house she's been renting, cars and extensive travel. The judge said it is believed that Sangha has no other legitimate source of employment and has the means to flee.

Sangha's lawyer argued that the prosecution's "media-friendly nickname" of "Ketamine Queen" cast blame on the defendant while trying to keep her client free on bond.

The judge pushed back, saying that Sangha has engaged in an "unrelenting return to drug dealing" after "her involvement in two overdose deaths."

Her next hearing has been scheduled for Oct. 15.

Perry died on Oct. 28, 2023, at the age of 54. He was discovered unresponsive in a jacuzzi at his Los Angeles home, police said. An autopsy report revealed he died from the acute effects of ketamine.

After his death, some of the co-conspirators allegedly talked about distancing themselves from the actor, according to the indictment. After Perry's death was reported in the news, Sangha instructed Fleming on Oct. 28, 2023, "Delete all our messages," according to the prosecutors.

Plasencia allegedly provided altered and falsified medical records, "purporting to show that he had a legitimate 'treatment plan' in place for Perry, with the intent to influence the investigation into Perry's death," in February and March in response to a request amid the federal investigation, prosecutors said.

The defendants allegedly used encrypted messaging and coded language referring to ketamine as "Dr. Pepper" to distribute their drugs, according to the indictment.

The indictment alleges that the two doctors were the initial sources of Perry's ketamine supply, but at one point federal officials believe the drugs became too expensive and Perry switched to a new source, including Sangha, a federal source said.

A search of Sangha's home following Perry's death revealed a "drug-selling emporium," including ketamine, methamphetamine, cocaine, scales and ledgers, Estrada said.

An 18-count superseding indictment returned by a grand jury on Wednesday charges Plasencia and Sangha with conspiracy to distribute ketamine and distribution of ketamine.

Plasencia is also charged with seven counts of distribution of ketamine and two counts of altering and falsifying documents or records related to the federal investigation.

Plasencia faces a maximum of 120 years in federal prison if convicted, while Sangha faces a maximum of life in prison, prosecutors said.

3 defendants in plea agreements

The three others charged in connection with Perry's death are in various stages of plea agreements, the DOJ said.

Chavez has agreed to plead guilty to one count of conspiracy to distribute ketamine, admitting in his plea agreement to selling ketamine to Plasencia, the DOJ said. Estrada said prosecutors filed a plea grant for him on Thursday. He is scheduled to be arraigned on Aug. 30 and faces up to 10 years in prison, prosecutors said.

Fleming and Iwamasa have signed plea agreements that have been entered, Estrada said. They face up to 25 and 15 years, respectively, when they are sentenced, prosecutors said.

Fleming pleaded guilty on Aug. 8 to one count of conspiracy to distribute ketamine and one count of distribution of ketamine resulting in death, admitting in court documents that he distributed 50 vials of ketamine that he obtained from Sangha to Iwamasa, including the ketamine that killed Perry, the DOJ said.

Iwamasa pleaded guilty on Aug. 7 to one count of conspiracy to distribute ketamine causing death. According to his plea agreement, Perry asked Iwamasa to help him procure ketamine in September 2023 and provided his assistant with "money, or promised to reimburse him, and directed him to find sources from whom to acquire the drugs."

Prosecutors alleged that Plasencia taught Iwamasa how to inject Perry with ketamine. Iwamasa "admitted to repeatedly injecting Perry with ketamine without medical training, including performing multiple injections on Perry on October 28, 2023 -- the day Perry died," the DOJ said.

Plea agreement recounts Perry's final hours

Iwamasa's plea agreement also details the day Perry died.

At Perry's direction, Iwamasa injected him with a shot of ketamine at approximately 8:30 a.m., then again at 12:45 p.m. while the actor watched a movie, according to the plea agreement.

About 40 minutes later, Perry asked his assistant to prepare the jacuzzi for him and "'shoot me up a big one,' referring to another shot of ketamine," the plea agreement stated.

Iwamasa admitted to administering the shot while Perry was in or near the jacuzzi, then leaving the house to run errands for him, according to the document.

"After returning to the residence, defendant found [Perry] face down in the jacuzzi and deceased," the document stated.

Perry had high levels of ketamine in his blood, likely lapsed into unconsciousness and then went underwater, according to the autopsy report.

He was reported to have been receiving ketamine infusions for depression and anxiety, with the most recent therapy coming 1 1/2 weeks before his death, according to the autopsy report. However, the medical examiner wrote the ketamine in his system at death could not have been from that infusion therapy, as ketamine's half-life is three to four hours or less.

The autopsy report also listed drowning, coronary artery disease and buprenorphine effects as contributing factors not related to the immediate cause of death. The manner of death was ruled an accident.

Prescription drugs and loose pills were found at his home, but nothing near where he was found dead, according to the autopsy report.

Multiple agencies have been investigating in the months since his death, including the DEA, Los Angeles Police Department, United States Postal Service and the U.S. Attorney's Office.

Perry was known for playing Chandler Bing on the hit sitcom "Friends," which ran from 1994 to 2004.

The actor's family, which includes his mother, Suzanne Morrison, and his stepfather, Keith Morrison, said in a statement Thursday that they are "heartbroken by Matthew's death, but it has helped to know law enforcement has taken his case very seriously. We look forward to justice taking its course."