The fire broke out in a third-floor apartment on East 78th Street near 2nd Avenue at around 1:30 a.m. Tuesday.
An eyewitness said he could see flames shooting from the building.
I could see fire coming right out of this part of this building. I could see it from my backyard, it was so close to where I am, even though our building wasn't affected. And then I came racing back down again and I see all of that fire and stuff," said Charlie Sunor, a neighbor.
One person's injuries were said to be life-threatening. The other two people were treated for minor injuries.
The fire was placed under control by 3:15 a.m.
The cause of the fire is under investigation.
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